Prevention Guidelines for Women 50–64

Here are the screening tests and immunizations that most women ages 50 to 64 need. A screening test is done to find possible health problems or diseases in people who don’t have any symptoms. The goal is to find a disease early so lifestyle changes can be made and you can be watched more closely to lower the risk of disease, or to find it early enough to treat it most effectively. Screening tests are not diagnostic. But they are used to find out if more testing is needed. Health counseling is vital, too. You and your healthcare provider may decide that a different schedule is best for you. But this plan can guide your discussion.

ScreeningWho needs itHow often
Type 2 diabetes or prediabetesAll adults starting at age 45 and adults without symptoms at any age who are overweight or obese and have 1 or more additional risk factors for diabetesAt least every 3 years
Alcohol misuseAll adultsAt routine exams
Blood pressureAll adultsYearly checkup if your blood pressure is normal. Normal blood pressure is less than 120/80 mmHg.1 If your blood pressure reading is higher than normal, follow the advice of your healthcare provider. 
 Breast cancerAll women2Yearly mammogram should be done until age 54. At age 55, switch to mammograms every other year. Or you may choose to continue yearly mammograms.2
Cervical cancerAll women, except those who have had a hysterectomy with removal of the cervix for reasons not related to cervical cancer and have no history of cervical cancer or serious precancerPap test every 3 years or Pap test with human papillomavirus (HPV) test every 5 years
ChlamydiaWomen at a higher risk for infectionAt routine exams
Colorectal cancerAll women of average risk in this age groupAccording to the American Cancer Society (ACS):For tests that find polyps and cancer:Flexible sigmoidoscopy every 5 years, orColonoscopy every 10 years, orCT colonography (virtual colonoscopy) every 5 yearsFor tests that primarily find cancer:Yearly fecal occult blood test, orYearly fecal immunochemical test every year, orStool DNA test, every 3 yearsYou will need a follow-up colonoscopy if you choose any test other than a colonoscopy and you have an abnormal result. Screening recommendations vary among expert groups. Talk with your doctor about which test is best for you.Some people should be screened using a different schedule because of their personal or family history. Talk with your doctor about your health history and what colorectal cancer screening schedule is best for you.
DepressionAll adults in clinical practices that have staff and systems in place to assure accurate diagnosis, effective treatment, and follow-upAt routine exams
GonorrheaSexually active women at a higher risk for infectionAt routine exams if at risk
Hepatitis CAdults at a higher risk; 1 time for those born between 1945 and 1965At routine exams if at risk
HIVAll womenAt routine exams if at risk
High cholesterol and triglyceridesAll women ages 45 and older at a higher risk for coronary artery diseaseAt least every 5 years
ObesityAll adultsAt routine exams
Lung cancerAdults age 55 to 80 who have smokedYearly screening in smokers with 30-pack per year history of smoking or who quits within 15 years
Osteoporosis, postmenopausal womenWomen at age 60 who are at a higher risk for fractures caused by osteoporosisCheck with your health care provider
SyphilisAdults at a higher risk for infectionAt routine exams if at risk
TuberculosisAdults at a higher risk for infectionCheck with your healthcare provider.
VisionAll adults5Check with your healthcare provider for exam frequency.
CounselingWho needs itHow often
Aspirin for prevention of cardiovascular problemsAt-risk adultsRecommended for women ages 55 to 79 years when the potential benefit of reducing strokes outweighs the potential harm of an increase in gastrointestinal bleedingWhen risk is identified; talk with your healthcare provider before starting
Breast cancer, chemopreventionWomen at high riskWhen risk is identified
BRCA mutation testing for breast and ovarian cancer susceptibilityWomen with a higher riskWhen risk is identified
Diet and exerciseWomen who are overweight or obeseWhen diagnosed
Sexually transmitted disease preventionAdults at a higher risk for infectionAt routine exams
Tobacco use and tobacco-related diseaseAll adultsEvery exam
ImmunizationWho needs itHow often
Haemophilus influenzae B typeAt risk adults1 to 3 doses
Tetanus/diphtheria/
pertussis (Td/Tdap) booster)
All adultsOne-time Tdap booster, then Td every 10 years
Measles, mumps, rubella (MMR)Adults in this age group through their late 50s who have no previous infection or documented vaccinations61 to 2 doses
Chickenpox (varicella)Adults ages 50 to 64 who have no previous infection or documented vaccinations62 doses; the second dose should be given at least 4 weeks after the first dose.
Flu vaccine (seasonal)All adultsYearly, when the vaccine becomes available in the community
Hepatitis A vaccinePeople at risk72 doses given at least 6 months apart
Hepatitis B vaccineHigh risk adults3 doses; second dose should be given 1 month after the first dose; the third dose should be given at least 2 months after the second dose (and at least 4 months after the first dose)
MeningococcalPeople at risk61 or more doses
Pneumococcal (PCV13)Pneumococcal (PPSV23)People at risk7PCV13: 1 dose ages 19 to 65 (protects against 13 types of pneumococcal bacteria)PPSV23: 1 to 2 doses through age 64, or 1 dose at 65 or older (protects against 23 types of pneumococcal bacteria)
ZosterAll women ages 60 and older61 dose
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